Error="[IOException] Access is denied.rn"

Error

[New File] File=“E:\Data\app.exe” Error="[IOException] Access is denied.rn"

Cause

This error means the OS is blocking access to the file you are trying to backup.
Likely causes are, the file is corrupted, has a virus, is encrypted or insufficient permissions.

Fix

Try to access the file through Windows explorer to see if that shows any other errors.